TB-500

Jump to section
Uses Dosing Protocol Reconst Inject Supplies Source Works Effects

TB-500

TB-500 is a synthetic peptide version of a naturally occurring protein fragment known as thymosin beta-4, currently being researched for its interaction with tissue repair, cellular migration, and recovery-related signaling pathways. Research has focused on its potential role in supporting connective tissue response, cellular regeneration, and inflammatory balance mechanisms.

Studies have also explored TB-500’s relationship with muscle recovery, angiogenesis, and tissue remodeling processes.

Recovery Tissue Repair Mobility

Common Research Uses

  • Tissue repair and recovery
  • Muscle and connective tissue studies
  • Inflammatory response and angiogenesis
  • Cellular migration and regenerative signaling

Typical Research Dosing

Daily Range: 500-1000 mcg
Frequency: Once daily
Common Cycle Length: Cycling data is limited. Reassses every 8-12 weeks
🧮 Calculate dose → 💧 Reconstitution steps 📥 View QuickStart card

Subcutaneous Protocol (5 mg + 3 mL BAC = ~1.67 mg/mL)

Phase Daily Dose (mcg) Units per Injection
Weeks 1-2 500 mcg once daily 30 units
Weeks 3-4 600 mcg once daily 36 units
Weeks 5-8 750 mcg once daily 45 units
Weeks 9-12 1000 mcg once daily 60 units

Based on reconstitution of 5 mg with 3 mL bacteriostatic water (~1.67 mg/mL).

Reconstitution Steps

Your Mix: 5 mg peptide + 3 mL bacteriostatic water = ~1.67 mg/mL
  1. Prep clean: Wash hands, use a clean surface, and gather supplies.
  2. Sanitize: Alcohol swab vial stoppers and allow to air-dry.
  3. Add diluent slowly: Inject bacteriostatic water down the vial wall to reduce foaming.
  4. Mix gently: Gently swirl or roll until fully dissolved. Do not shake.
  5. Label: Write compound name, date, and concentration (mg/mL).
  6. Store appropriately: Store according to supplier guidance and maintain sterile technique.

Educational reference only

Injection Technique

General subcutaneous guidance from clinical best-practice resources.

  • Allow the peptide to reach room temperature before injection.
  • Clean the vial stopper and injection site with alcohol and allow to fully dry.
  • Pinch a small skinfold and insert the needle at a 45–90° angle into subcutaneous tissue.
  • Do not aspirate for subcutaneous injections; inject slowly and steadily.
  • Rotate injection sites systematically (abdomen, thighs, upper arms) to avoid lipohypertrophy.
  • Inject slowly to help minimize any stinging sensation.

This information is provided for educational reference only and reflects general clinical best practices.

Supplies Needed (Auto Calculator)

Inventory planning tool. Choose presets or enter your own values.

Preset weeks
Preset vials (5 mg each)
Syringes (U-100)
—
— / week
Bacteriostatic water
— mL
— bottle(s)
Alcohol swabs
—
— box(es)
Shop at MADDOG Peps →

Notes: Syringes = (weeks × 7 × injections/day). Swabs = (syringes × swabs/injection). BAC = (vials × mL per vial). Bottles/boxes are rounded up.

How It Works

TB-500 is a synthetic peptide modeled after thymosin beta-4, a naturally occurring protein involved in cellular repair and regeneration processes throughout the body. Research suggests it plays a role in supporting cell migration, tissue remodeling, and recovery-related signaling pathways following physical stress or tissue damage.

Studies have explored TB-500’s interaction with actin, a protein involved in cell structure and movement, which may contribute to cellular migration and tissue repair activity. Researchers have also examined its potential influence on angiogenesis, collagen organization, and inflammatory signaling pathways associated with recovery processes.

At the cellular and systemic level, TB-500 has been studied for its relationship with connective tissue integrity, muscle recovery, and localized tissue remodeling. Additional research has investigated its potential role in supporting flexibility, mobility-related tissue response, and overall regenerative signaling activity.

Unlike compounds that primarily rely on hormonal mechanisms, TB-500 is being researched for its peptide-based regenerative and recovery-focused signaling pathways tied to tissue maintenance and cellular repair.

Commonly Reported Side Effects

  • Fatigue
  • Nausea
  • Mild Headache
  • Lightheadedness
  • Injection site reactions
  • Temporary muscle tightness

These effects are based on commonly reported research observations and may vary by individual.

↑